• FTSE 100 down 0.3%, FTSE 250 flat
• Bank of England expected to keep rates at 4% amid inflation data
• Energy and pharma stocks decline
• Financials and metal miners gain, offsetting losses in other sectors

Nov 6 (Reuters) - UK's main stock indices were little changed on Thursday as sterling steadied near multi-month lows, with traders pausing for breath ahead of the Bank of England's interest rate call.

The central bank is widely expected to keep rates at 4% when it announces its decision at 1200 GMT, and its tone will be crucial to guiding sentiment as traders navigate the final stretch of the year.

Sign up here.

Still, a shift in stance from Goldman Sachs, which last week said it now expects a rate cut after softer inflation and wage data, has stirred some speculation.

The blue-chip FTSE 100 index (.FTSE) , opens new tab was 0.3% lower, retreating from a record high in the previous session, as gains in financials and metal miners were offset by a selloff in energy and pharma. The midcap index (.FTMC) , opens new tab was flat.

Oil and gas companies' shares lost ground despite a rise in oil prices, with BP (BP.L) , opens new tab ticking 0.7% lower and Shell (SHEL.L) , opens new tab down 0.4%.

Shares of Healthcare and medical equipment and services also slipped, with GSK plc (GSK.L) , opens new tab down 0.6%. Smith & Nephew PLC (SN.L) , opens new tab plunged 10% after it missed market expectations for quarterly revenue due to weakness in its U.S. knee implants business.

Trading in AstraZeneca (AZN.L) , opens new tab was choppy, with shares last trading 0.2% lower. The pharma giant reported better-than-expected third-quarter profit on Thursday, boosted by strong sales in cancer and heart-related drugs.

Financials led the gainers, with HSBC Holdings (HSBA.L) , opens new tab, Standard Chartered (STAN.L) , opens new tab and Barclays PLC (BARC.L) , opens new tab up 0.9%, 1.1% and 1.5%, respectively.

The Financial Times reported that Chancellor Rachel Reeves was set to spare them from a punitive budget tax raid.

Metal miners climbed as copper and iron ore snapped a four-day losing streak. Rio Tinto (RIO.L) , opens new tab rose 0.3% and Glencore PLC (GLEN.L) , opens new tab jumped 2.2%.

Among consumer staples, Unilever (ULVR.L) , opens new tab dropped 1.9%. Diageo (DGE.L) , opens new tab fell 5% after trimming its 2026 sales and profit forecast.

https://www.reuters.com/business/finance/uk-stocks-steady-traders-await-rate-cues-sterling-holds-near-lows-2025-11-06/